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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 16, 1986 - Issue 3
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Original Articles

An Asymmetric Strecker Synthesis of (R)-(+)-2-Methyl-3-Phenylalanine: An Efficient Preparation

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Pages 337-342 | Published online: 19 Dec 2006
 

Abstract

A convenient four-step asymmetric Strecker synthesis, utilizing (S)-(-)-1-phenylethylamine as the chiral auxiliary reagent, is described for the preparation of (R)-(+)-2-methyl-3-phenylalanine in >98% enantiomeric excess.

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