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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 16, 1986 - Issue 8
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Original Articles

Selective Reduction of Carboxylic Acid Esters in the Presence of a Five-Membered Cyclic Sulfone

Wayne K. Anderson Department of Medicinal Chemistry, School of Pharmacy, State University of New York at Buffalo, Buffalo, NY, 14260
&
Robert H. Mach Department of Medicinal Chemistry, School of Pharmacy, State University of New York at Buffalo, Buffalo, NY, 14260
Pages 911-915 | Published online: 19 Dec 2006
 
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Abstract

Carboxylic acid esters can be selectively reduced in the presence of five-membered cyclic sulfones using AlH3. ether in anhydrous THF at cold temperatures.

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