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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 17, 1987 - Issue 13
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Original Articles

Sodium Formaldehyde Sulphoxylate an Efficient Reagent For The Reduction of α-Haloketones

Alan R. Harris Chemical Process R & D Department, Fisons plc, Pharmaceutical Division, R & D Laboratories, Bakewell Road, Loughborough, Leics, England, LEII ORH
Pages 1587-1592 | Published online: 06 Dec 2006
 
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Abstract

Sodium formaldehyde sulphoxylate is shown to be an inexpensive, efficient reagent for the dehalogenation of phenacyl halides and other α-haloketones. Some possible mechanisms for the reduction are discussed.

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