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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 5-6
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Original Articles

A Facile Synthesis of 1,4-Diketones from Organolithium Reagents and N,N,N′,N′-Tetramethylsuccinamide

Wai-Yee Leung Department of Chemistry, Michigan State University, East Lansing, Michigan, 48824
&
Eugene Legoff Department of Chemistry, Michigan State University, East Lansing, Michigan, 48824
Pages 787-792 | Received 20 Jul 1988, Published online: 24 Oct 2006
 
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Abstract

The reaction of organolithium reagents (alkyl, aryl, heteroaryl) with N,N,N′,N′-tetramethylsuccinamide at 0 °C gives good yields of the corresponding 1,4-diketones.

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