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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 5-6
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Original Articles

A Convenient Synthesis of 5-Aryltropones

Richard M. Keenan Department of Medicinal Chemistry, Smith Kline & French Laboratories, 709 Swedeland Road, Swedeland, Pennsylvania, 19479
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Lawrence I. Kruse Department of Medicinal Chemistry, Smith Kline & French Laboratories, 709 Swedeland Road, Swedeland, Pennsylvania, 19479; Department of Medicinal Chemistry, Smith Kline & French Research Ltd, The Frythe, Welwyn, Hertfordshire, AL6 9Ar, UK
Pages 793-798 | Received 30 Jun 1988, Published online: 24 Oct 2006
 
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Abstract

2-Methoxy-5-[[(trifluoromethyl)sulfonyl]oxy]tropone was coupled to a variety of arylzinc chlorides in the presence of a palladium catalyst to furnish 5-aryltropones in good to excellent yields.

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