Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 5-6
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Original Articles

The Stereoselective Aldol Condensation of α-Fluoroacetates

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Pages 1081-1090 | Received 29 Aug 1988, Published online: 24 Oct 2006
 

Abstract

2,6-Di-t-butyl-4-methylphenyl(BHT) and benzyl α-fluoroacetates were converted to their lithium enolates and were utilized in the aldol condensation. The improved diastereoselectivity found with the BHT esters is thought to arise from of equilibration of the aldol product rather than stereoselective enolate formation.

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