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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 9-10
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Original Articles

Quantitative Synthesis of L Or D N2-Tertbutoxycarbonyl- 2,3-DIAMINOPROPANOIC ACID FROM PROTECTED L OR D SERINE-β -LACTONE

N. Kucharczyk Laboratoire de Bioorganique et Biotechnologies, E. N.S.C.P. II, rue Pierre et Marie Curie 75231, Paris, Cedex, 05, France
,
B. Badet Laboratoire de Bioorganique et Biotechnologies, E. N.S.C.P. II, rue Pierre et Marie Curie 75231, Paris, Cedex, 05, France
&
F. Le Goffic Laboratoire de Bioorganique et Biotechnologies, E. N.S.C.P. II, rue Pierre et Marie Curie 75231, Paris, Cedex, 05, France
Pages 1603-1609 | Received 17 Nov 1988, Published online: 24 Oct 2006
 
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Abstract

The reaction of ammonia on protected L or D serine-β-lactone was reinvestigated. An easy synthesis of N2 -tertbutoxycarbonyl-L-2,3-diaminopropanoic acid (and D enantiomer). an important precursor of several antibiotics is proposed.

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