A Convenient Preparation of Benzylic Homopropargylic Alcohols Via Allenyllithium Reagents

Abstract

Among the distinctive methods providing acetylenic functions^1-3 reactions employing anionic propargylic equivalents opposed to electrophilic species provide a potentially valuable route to propargylic derivatives^4-6. Their general applicability in synthetic processes, however, is frequently hampered by the tendency of such nucleophiles to produce troublesome mixtures of isomeric acetylenic and allenic products in moderate yields.