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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 11-12
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Original Articles

A Convenient Synthesis of β-Hydroxyesters from Andehydes or Ketones and α-Bromoesters BrCH2-Coor', R' Being A Long Carbon Chain

Jean-François Chollet Laboratoire de Synthèse Organique, Associé au CNRS
,
Léone Miginiac Laboratoire de Synthèse Organique, Associé au CNRS
,
Gérard Picotin Laboratoire de Chlmie des Organométalliques, Associé au CNRS, Université de Poitiers, 86022, Poitiers
&
Philippe Miginiac Laboratoire de Chlmie des Organométalliques, Associé au CNRS, Université de Poitiers, 86022, Poitiers
Pages 2167-2173 | Received 17 Feb 1989, Published online: 24 Oct 2006
 
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Abstract

The Reformatsky reaction between aldehydes or ketones and bromoesters BrCH2 COOR (R' nC8 H17, nC12 H25) proceeds readily in ether provided activated zinc is used.

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