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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 17
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Original Articles

Synthesis of Ureidocarboxylic Acids and Hydantoins by Reaction of Aminocarboxylic Acids or Their Esters with Trichloroacetamides

I. A. Atanassova Institute of Organic Chemistry, BAS, Laboratory of Biologically Active Substances, 4002, Plovdiv, P.O. Box 27, Bulgaria
,
J. S. Petrov Institute of Organic Chemistry, BAS, Laboratory of Biologically Active Substances, 4002, Plovdiv, P.O. Box 27, Bulgaria
,
A. N. Balabanova Institute of Organic Chemistry, BAS, Laboratory of Biologically Active Substances, 4002, Plovdiv, P.O. Box 27, Bulgaria
&
N. M. Mollov Institute of Organic Chemistry, BAS, Laboratory of Biologically Active Substances, 4002, Plovdiv, P.O. Box 27, Bulgaria
Pages 2947-2954 | Received 15 May 1989, Published online: 24 Oct 2006
 
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Abstract

The reactivity of N-aryltrichloroacetamides as in situ generating isocyanates is used in the reaction with aminocarboxylic acids and their esters. N-aryl ureido-carboxylic acids, their esters or hydantoins are the obtained compounds.

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