Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 17
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Original Articles

Interaction of Nitromethane with Esters and Amides of 2-Oxo-2H-1-benzopyrane-3-carboxylic Acid

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Pages 2963-2975 | Received 15 May 1989, Published online: 24 Oct 2006
 

Abstract

The reaction of esters as well as N,N-disubstituted amides of 2-oxo = 2H-1-benzopyran-3-carboxylic acid with nitromethane in the presence of potassium fluoride leads to the corresponding diesters and ester -amides of 2-carboxy-3-(2-hydroxyphenyl)-4-ni trobutyric acid (2a-m). The configuration and preferable conformation of the ester-amides are discussed.

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