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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 15
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Original Articles

Methylenation of N-Acylheterocycles

S. Wattanasin Sandoz Research Institute, East Hanover, New Jersey, 07936
&
F. G. Kathawala Sandoz Research Institute, East Hanover, New Jersey, 07936
Pages 2659-2664 | Received 28 Mar 1989, Published online: 24 Oct 2006
 
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Abstract

Various N-alkenyl heterocycles can be obtained in modest to good yields by methylenation of N-acylheterocycles with the Tebbe reagent. The reaction provides a useful method for introducing the isopropyl group on the nitrogen of aromatic heterocycles.

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