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Volume 20, Issue 20
synthesis of Enantiomerically Pure amino ....

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Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 20, 1990 - Issue 20

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Original Articles

synthesis of Enantiomerically Pure amino acids containing a 2-Amino-4-thiazolyl side chain

William C. Patt Chemistry Department Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan, 48105

Richard W. Skeean Chemistry Department Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan, 48105

Bruce A. Steinbaugh Chemistry Department Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan, 48105

Pages 3097-3102 | Received 06 Aug 1990, Published online: 24 Oct 2006

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https://doi.org/10.1080/00397919008051532

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Abstract

Enantiomerically pure 2-amino-4-thiazolyl containing amino acids were readily synthesized from commercially available derivatives of aspartic acid and glutamic acid, via reaction with diazomethane and further cyclization with thiourea.

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