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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 2
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Original Articles

Preparation of (-)-(1R, 2S)-1-Phenylpropane-1,2-Diol by Fermenting Baker's Yeast Reduction of 1-Phenyl-1,2-propanedione

Eugěnia Cristina Souza Brenelli Universidade Estadual de Campinas, Instituto de Química, 13081, Campinas, SP, Brasil
,
Paulo José Samenho Moran Universidade Estadual de Campinas, Instituto de Química, 13081, Campinas, SP, Brasil
&
J. Augusto R. Rodrigues Universidade Estadual de Campinas, Instituto de Química, 13081, Campinas, SP, Brasil
Pages 261-266 | Received 18 Sep 1989, Published online: 24 Oct 2006
 
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Abstract

Baker's yeast fermentation of diketone 1 can give the optically actives alcohols 2 or 3 depending on the procedure used. We describe the preparation of the diol 3 in 67–88% chemical yield.

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