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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 2
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Original Articles

Improved Procedure for the Reduction of N-Acyloxazolidinones

Thomas D. Penning Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
,
Stevan W. Djuric Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
,
Richard A. Haack Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
,
Vincent J. Kalish Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
,
Julie M. Miyashiro Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
,
Bruce W. Rowell Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
&
Stella S. Yu Searle Research and Development, Division of G.D. Searle & Co., Skokie, Illinois, 60077
 show all
Pages 307-312 | Received 01 Oct 1989, Published online: 24 Oct 2006
 
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Abstract

Lithium borohydride in the presence of one equivalent of water has been found to be an efficient agent for the reduction of sterically hindered acyloxazolidinones to the corresponding primary alcohol.

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