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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 5
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Original Articles

An Improved Procedure for Cyclisation of Chalcones to Flavanones Using Celite Supported Potassium Fluoride in Methanol: Total Synthesis of Bavachinin

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Pages 649-657 | Received 26 Oct 1989, Published online: 24 Oct 2006
 

Abstract

Chalcones may be cyclised to the corresponding flavanones by stirring with KF-celite suspended in methanol at reflux. This method gives consistently higher conversion than other reported procedures and its utility is illustrated by the synthesis of the linear prenylated flavanone bavachinin.

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