Lewis Acid-Mediated Addition of Lithiated Alkyl Phenyl Sulphones and Oxiranes. A Method for Synthesis of α, β-Unsaturated Ketones

Abstract

Efficiency of the reaction of lithiated alkyl aryl sulphones (1–4) with oxiranes (5, 6) is increased by the presence of BF₃ or CeCl₃. The respective adducts (7–14) were transformed into α,β-unsaturated ketones (15–22) with high yields.