Abstract
Coupling reactions of trimethylsilylacetylene and vinylic, aromatic or heteroaromatic bromides can be carried out in very short time and with excellent yield using piperidine as a solvent and very small amounts of tetrakis(triphenylphosphine)palladium and copper(I)iodide (0.1 to 0.3 g on 100 mmol scale) as catalysts.