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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 4
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Original Articles

A Mild and Convenient Oxidation of Aryl Nitriles to Aryl Amides by Aqueous Sodium Perborate

Kathryn L. Reed Department of Chemistry, University of Central Florida, Orlando, FL, 32816
,
John T. Gupton Department of Chemistry, University of Central Florida, Orlando, FL, 32816
&
Traci L. Solarz Department of Chemistry, University of Central Florida, Orlando, FL, 32816
Pages 563-571 | Published online: 24 Oct 2006
 
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Abstract

A series of benzonitriles has been reacted with sodium perborate in water and a cosolvent to produce the corresponding amides in good yield. The procedure is a mild and convenient alternative for the synthesis of aryl amides.

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