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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 10-11
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Original Articles

Stereoselective Total Synthesis of 10-(R)-Hydroxy-8E,12Z-octadecadienoic Acid: The Fungitoxic Compound in Timothy Plant

A V Rama Rao Indian Institute of Chemical Technology, Hyderabad, 500 007, India
,
Ch V N S Varaprasad Indian Institute of Chemical Technology, Hyderabad, 500 007, India
&
E Rajarathnam Reddy Indian Institute of Chemical Technology, Hyderabad, 500 007, India; R&D Division, Smithkline Beecham, Pennsylvania, USA
Pages 1143-1152 | Received 25 Feb 1991, Published online: 16 Feb 2007
 
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Abstract

A convenient synthesis of 10-(R)-hydroxy-8E,12Z-octadecadienoic acid, the fungitoxic compound in the timothy plant (Phleum pratense) against leaf spot disease is described utilising D-xylose as chiral source.

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