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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 12-13
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Original Articles

Asymmetric Synthesis of 2-Arylpropionic Acids

Asensio González Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028, Barcelona, Spain
Pages 1353-1360 | Received 02 Apr 1991, Published online: 23 Sep 2006
 
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Abstract

The preparation of (S)-2-(6-methoxy-2-naphtyl)propionic acid (S-Naproxen) 1 and (S)-2-(4-isobutylphenyl)propionic acid (S-Ibuprofen) 2, based on asymmetric alkylation of oxazolidiones 9 and 14, is reported.

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