![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
Anhydrous lithium bromide has been successfully used as an additive instead of hexamethylphosphoric triamide in the O-trimethylsilylation of enolates generated by copper halide-catalyzed reaction of Grignard reagents with a number of α, β-unsaturated carbonyl compounds. Some conjugate additions also proceed satisfactorily in the absence of lithium bromide.