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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 21, 1991 - Issue 18-19
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Original Articles

A Preparative Synthesis of 1-Amino-3-hydroxypropylphosphonic Acid (Phosphonic Analogue of Homoserine)

Anne-Marie Laboratoire de Bioorganique et Biotechnologies U.A. C.N.R.S., 1389, E.N.S.C.P., 11 rue P. et M. Curie, 75231, Paris Cédex 05, France
,
Chollet-Gravey Laboratoire de Bioorganique et Biotechnologies U.A. C.N.R.S., 1389, E.N.S.C.P., 11 rue P. et M. Curie, 75231, Paris Cédex 05, France
,
Liliane Vo-Quang Laboratoire de Bioorganique et Biotechnologies U.A. C.N.R.S., 1389, E.N.S.C.P., 11 rue P. et M. Curie, 75231, Paris Cédex 05, France
,
Yen Vo-Quang Laboratoire de Bioorganique et Biotechnologies U.A. C.N.R.S., 1389, E.N.S.C.P., 11 rue P. et M. Curie, 75231, Paris Cédex 05, France
&
Francois Le Goffic Laboratoire de Bioorganique et Biotechnologies U.A. C.N.R.S., 1389, E.N.S.C.P., 11 rue P. et M. Curie, 75231, Paris Cédex 05, France
Pages 1847-1858 | Received 15 May 1991, Published online: 23 Sep 2006
 
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Abstract

A novel procedure for the preparation of the phosphonic analogue of homoserine is described starting from the commercially available 4-acetoxy-azetidin-2-one.

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