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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 22, 1992 - Issue 16
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Original Articles

A New One Step Synthetic Approach to the Isoxazolo[4,5-b]Pyridine System

Rodolfo Nesi Dipartimento di Chimica Organica „Ugo Schiff“-Centro di Studio del CNR sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, Università di Firenze, Via Gino Capponi 9, I-50121, Firenze, Italy
,
Donatella Giomi Dipartimento di Chimica Organica „Ugo Schiff“-Centro di Studio del CNR sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, Università di Firenze, Via Gino Capponi 9, I-50121, Firenze, Italy
,
Stefania Turchi Dipartimento di Chimica Organica „Ugo Schiff“-Centro di Studio del CNR sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, Università di Firenze, Via Gino Capponi 9, I-50121, Firenze, Italy
,
Piero Tedeschi Dipartimento di Chimica Organica „Ugo Schiff“-Centro di Studio del CNR sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, Università di Firenze, Via Gino Capponi 9, I-50121, Firenze, Italy
&
Fabio Ponticelli Istituto di Chimica Organica dell'Università, Pian dei Mantelli 44, I-53100, Siena, Italy
Pages 2349-2355 | Received 13 Apr 1992, Published online: 23 Sep 2006
 
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Abstract

A convenient direct entry to the title ring system by condensation-cyclization processes of 3,5-dimethyl-4-nitroisoxazole (1) with the enamines 2 and 8 is reported; some reactions of the resulting N-oxides 5 and 10 are also described.

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