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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 22, 1992 - Issue 1
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Original Articles

Synthesis of 1-Phenyl-2-acyl-tetrahydroisoquinolines by Intermolecular α-Amidoalkylation Reaction

Atanas P. Venkov Department of Chemistry, University of Plovdiv, 4000, Plovdiv, Bulgaria
,
Stela M. Statkova Department of Chemistry, University of Plovdiv, 4000, Plovdiv, Bulgaria
&
Ilian I. Ivanov Department of Chemistry, University of Plovdiv, 4000, Plovdiv, Bulgaria
Pages 125-134 | Received 09 Jul 1991, Published online: 23 Sep 2006
 
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Abstract

1-Phenyl-2-acyl-tetrahydroisoquinolines are obtained by an intermolecular α-amidoalkylation reaction of aromatics 4 with the adducts 3 of 3,4-dihydroiso-quinolines and acyl chlorides.

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