Syntheses of epi-β-Santalene, β-Santalene and an Isomer of β-Santalene with 4-Methyl-4-pentenyl Side Chain

Abstract

The olfactory characteristics of East Indian Sandalwood oil is mainly due to its major components α-santalol (1) and β-santalol (2), while many of the components like β-santalene (3) and epi-β-santalene (4) also contribute to the perfumery

properties¹. Since the pioneering work of Corey², Brieger³ and Money⁴ a number of syntheses of these compounds have appeared^5,6. Of late there has been great interest in the synthesis of certain minor components of the oil, like the isomer of β-santalene with 4-methyl-4-pentenyl side chain (5).