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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 9
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Original Articles

Use of Tetrahydro-2H-1,3-Oxazinones as Aminopropylation Agents

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Pages 1329-1338 | Received 17 Nov 1992, Published online: 24 Sep 2006
 

Abstract

Treatment of tetrahydro-2H-1,3-oxazin-2-one (1) or the 3-methyl derivative 2 with aniline salts or thiophenols at 180 °C affords the corresponding N-aryl-1,3-propanediamines 3 or 3-(arylthio)propanamines 4 in good yields.

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