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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 11
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Original Articles

An Improved Synthesis of 8-Bromo-2′-deoxyguanosine

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Pages 1611-1615 | Received 05 Jan 1993, Published online: 23 Sep 2006
 

Abstract

A new synthesis of 8-bromo-2′-deoxyguanosine, a key intermediate in the synthesis of the mutagenic DNA adduct 8-oxo-2′-deoxyguanosine is described. The advantages of this method are significantly improved yields and ease of isolation.

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