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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 16
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Original Articles

A Convenient Procedure for the Preparation of Alkyl Nitriles from Alkyl Halides. Acetone Cyanohydrin as an In Situ Source of Cyanide Ion

Paul Dowd Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, 15260, USA
,
Bogdan K. Wilk Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, 15260, USA; Wyeth-Ayerst Research, Rouses Point, NY, 12979
&
Marek Wlostowski Warsaw Technical University, ul. Koszykowa 75, 00-662, Warsaw, Poland
Pages 2323-2329 | Published online: 23 Sep 2006
 
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Abstract

A convenient preparation of alkyl nitriles from alkyl halides is described. Acetone cyanohydrin is employed as the source of cyanide ion.

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