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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 19
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Original Articles

A Convenient Synthesis of 9-Hydroxy-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indole from 7-Methoxyindole

Francesco Santangelo Medicinal Chemistry Department, Zambon Group S.p.A., Via Lillo del Duca 10, 20091, Bresso (Milan), Italy
,
Cesare Casagrande Medicinal Chemistry Department, Zambon Group S.p.A., Via Lillo del Duca 10, 20091, Bresso (Milan), Italy
,
Gabriele Norcini Medicinal Chemistry Department, Zambon Group S.p.A., Via Lillo del Duca 10, 20091, Bresso (Milan), Italy
&
Fulvio Gerli Medicinal Chemistry Department, Zambon Group S.p.A., Via Lillo del Duca 10, 20091, Bresso (Milan), Italy
Pages 2717-2725 | Received 07 Apr 1993, Published online: 23 Sep 2006
 
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Abstract

The title compound was prepared with a route which is characterized by selective carboxylation in position four of 7-methoxyindole. Brief biological results are reported.

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