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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 19
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Original Articles

Improved Syntheses of 2-Bromonicotinaldehyde and Acid

Patricia Melnyk Institut de Chimie des Substances Naturelles - C.N.R.S., Avenue de la Terrasse, 91198, Gif-sur-Yvette, France
,
Jeannette Gasche Institut de Chimie des Substances Naturelles - C.N.R.S., Avenue de la Terrasse, 91198, Gif-sur-Yvette, France
&
Claude Thal Institut de Chimie des Substances Naturelles - C.N.R.S., Avenue de la Terrasse, 91198, Gif-sur-Yvette, France
Pages 2727-2730 | Received 14 Apr 1993, Published online: 23 Sep 2006
 
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Abstract

Synthetically useful 2-bromonicotinaldehyde and 2-bromonicotinic acid can be conveniently prepared in high yield from the directed ortho metalation of 2-bromopyridine.

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