Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 23, 1993 - Issue 8
Submit an article Journal homepage
133
Views
10
CrossRef citations to date
0
Altmetric
Original Articles

A Practical Synthesis of Both Enantiomers of 1-Amino-2-propanol and Propylene Oxide

Kai Rossen Department of Process Research, Merck Research Laboratories, P. O. Box 2000, Rahway, N. J., 07065
,
Pamela M. Simpson Department of Process Research, Merck Research Laboratories, P. O. Box 2000, Rahway, N. J., 07065
&
Kenneth M. Wells Department of Process Research, Merck Research Laboratories, P. O. Box 2000, Rahway, N. J., 07065
Pages 1071-1074 | Received 26 Oct 1992, Published online: 23 Sep 2006
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A practical large-scale synthesis of both enantiomers of 1-amino-2-propanol 1 from L- and D-threonine is described. Greater than 99% e.e. propylene oxide 2 is obtained from 1 through a diazotization under basic conditions.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.