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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 22
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Original Articles

A Facile Synthesis of 5-Phenylimidazo- [4,5-c]-[1,8]naphthyridin-4(5H)-one

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Pages 3289-3296 | Received 25 Feb 1994, Published online: 23 Sep 2006
 

Abstract

1-Phenyl-3-nitroso-4-amino-1,8-naphthyridin-2(1H)-one (9) was prepared on a large scale and was converted to 5-phenyl-imidazo[4,5-c] [1,8]naphthyridin-4(5H)-one (KF17625, 1) which exhibits potent antiasthmatic activity.

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