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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 17
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Original Articles

Preparation of N-Boc N-Alkyl Glycines for Peptoid Synthesis

, , , , , & show all
Pages 2429-2435 | Received 10 Mar 1994, Published online: 16 Feb 2007
 

Abstract

A series of N-tert-butoxycarbonylated N-allyl, N-propargyl, N-benzyl or branched N-alkyl glycines, useful building blocks for the synthesis of N-alkyl glycine oligomers, have been prepared by N-alkylation of N-Boc glycine or by a two-step method: reductive alkylation and tert-butoxycarbonylation.

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