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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 10
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Original Articles

A New Method for the Preparation of β-Hydroxy Nitriles: Transformation of 3-Bromo-2-isoxazolines to β-Hydroxy Nitriles by Treatment of Alkanethiolates

Min Hyo Seo Department of Chemistry
,
Youn Young Lee Department of Chemistry
&
Yang Mo Goo Department of Pharmacy, Seoul National University, Seoul, 151-742, Korea
Pages 1433-1439 | Received 11 Aug 1993, Published online: 23 Sep 2006
 
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Abstract

3-Bromo-2-isoxazolines are transformed to β-hydroxy nitriles in good yields by treatment with alkanethiolates under a very mild condition.

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