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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 1
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Original Articles

β-Cyclodextrin-TEBA: A New Catalyst System For Selective Synthesis of α-Hydroxyacids

Cheng-He Zhou Department of Chemistry, Sichuan University, Chengdu, 610064, P. R. China
,
De-Qi Yuan Department of Chemistry, Sichuan University, Chengdu, 610064, P. R. China
&
Ru-Gang Xie Department of Chemistry, Sichuan University, Chengdu, 610064, P. R. China
Pages 43-46 | Received 24 Jun 1993, Published online: 23 Sep 2006
 
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Abstract

The presence of β-cyclodextrin (β-CD) and triethylbenzyl ammonium chloride (TEBA) favors the one-pot reaction of aromatic aldehydes, chloroform and sodium hydroxide to give α-hydroxyarylacetic acids in 81% ∼ 89% yields.

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