Asymmetric Hydrocyanation of 3-Phenoxybenzaldehyde Catalyzed by Polymer-Bound Cyclic Dipeptides

Abstract

The polymer-bound catalyst 3a-e inserted some spacer ([-NHCO(CH_{2 10- n}; n = 0,1,2,3,4) connecting the catalytic moiety [cyclo(-(S)-Phe-(S)-His)], [(S,S)-1] and 2% cross-linked Merrifield's polymer, have been prepared and their catalytic efficiency for the enantioselective hydrocyanation of 3-phenoxybenzaldehyde was studied.