Highly Selective Amidation of Benzylic Alcohols with Nitriles. A Modified Ritter Reaction: Synthetic Communications: Vol 24, No 5

Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 24, 1994 - Issue 5

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Abstract

Benzyl alcohols react selectively with different nitriles in the presence of a catalytic amount of boron trifluoride and produce amides in high yields. Deactivated p-nitrobenzyl, allylic, primary, secondary, and tertiary saturated alcohols do not react.

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Highly Selective Amidation of Benzylic Alcohols with Nitriles. A Modified Ritter Reaction

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Highly Selective Amidation of Benzylic Alcohols with Nitriles. A Modified Ritter Reaction

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