New Experiments in the Reductive N-Alkylation and N-Peralkylation of Aromatic Amines

G. Verardo Department of Chemical Sciences and Technologies, University of Udine, I-33100, Udine, Italy

A. G. Giumanini Department of Chemical Sciences and Technologies, University of Udine, I-33100, Udine, Italy

P. Strazzolini Department of Chemical Sciences and Technologies, University of Udine, I-33100, Udine, Italy

Abstract

Some secondary and primary aromatic amines were variously N-alkylated and N-peralkylated by the aldehyde-sodium borohydride procedure in acidic aqueous solution. The procedure lends itself to the α-mono and α,α'-dideuterium labelling of the new N-substituent(s).

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New Experiments in the Reductive N-Alkylation and N-Peralkylation of Aromatic Amines

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New Experiments in the Reductive N-Alkylation and N-Peralkylation of Aromatic Amines

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