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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 2
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Original Articles

A Novel Synthetic Route to 1,3-Disubstituted Naphthalenes

Lucjan Strekowski Department of Chemistry, Georgia State University, Atlanta, Georgia, 30303, USA
,
Roman L. Wydra Department of Chemistry, Georgia State University, Atlanta, Georgia, 30303, USA
,
Alexander S. Kiselyov Department of Chemistry, Georgia State University, Atlanta, Georgia, 30303, USA
,
John H. Baird Department of Chemistry, Georgia State University, Atlanta, Georgia, 30303, USA
,
Andrew Burritt Department of Chemistry, University of Canterbury, Christchurch, New Zealand
&
James M. Coxon Department of Chemistry, University of Canterbury, Christchurch, New Zealand
Pages 257-266 | Received 08 Jul 1993, Published online: 23 Sep 2006
 
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Abstract

1-(2-Substituted 1-propenyl)-2-(trifluoromethyl)benzenes are cyclized to 3-substituted 1-(4-methylpiperazino)naphthalenes in a lithium 4-methylpiperazide-mediated reaction that involves the trifluoromethyl group.

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