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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 7
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Original Articles

Synthesis of Long Chain ω-Aralkylbromides

M. A. Forth SmithKline Beecham Pharmaceuticals, Old Powder Mills, Leigh, Nr Tonbridge, Kent, TN11 9AN, England
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S. Smith SmithKline Beecham Pharmaceuticals, Old Powder Mills, Leigh, Nr Tonbridge, Kent, TN11 9AN, England
Pages 951-959 | Received 09 Sep 1993, Published online: 23 Sep 2006
 
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Abstract

-1-Iodo-4-acetoxybutane is a useful 4 carbon synthon which reacts selectively with Grignards under copper catalysis. The immediate products are converted to bromides.

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