Synthesis of Metal-Chelating Polymerizable Phospholipids

Alok Singh Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington, DC, 20375-5438

L.-I. Tsao Department of Biochemistry, Georgetown University, Washington, DC, 20040

Dhananjay B. Puranik Department of Biochemistry, Georgetown University, Washington, DC, 20040

Abstract

Two routes for the synthesis of metal chelating phospholipids are reported. An iminodiacetic acid functionality served as metal chelating site in the polar headgroup region of a phospholipid while a tricosa-10,12-diynoyl group linked to the glycerol backbone, made up the polymerizable hydrocarbon region.

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Synthesis of Metal-Chelating Polymerizable Phospholipids

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Synthesis of Metal-Chelating Polymerizable Phospholipids

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