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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 19
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Original Articles

Zinc-Promoted Barbier-Type Reaction of Propargyl Bromide with Aldehydes in Aqueous Media

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Pages 2923-2928 | Received 11 Jan 1995, Published online: 16 Feb 2007
 

Abstract

In the prese of metallic zinc, propargyl bromide is found to react with aldehydes at room temperature in tetrahydrofurane-saturated aqueous ammonium chloride (5:2) to afford the corresponding homopropargylic alcohols in moderate to high yields together with small amounts of α-allenic alchohols.

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