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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 19
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Original Articles

Selective Reduction of Nitrones and Nitroxides to Functionalized Secondary Amines

Cecília P. Sár Central Research Laboratory, Chemistry, University of Pécs, H-7643, Pécs, PO Box 99, Hungary; Chemistry and Biochemistry Department, Janus Pannonius University, H- 7601, Pécs, Hungary
,
Tamás Kálai Central Research Laboratory, Chemistry, University of Pécs, H-7643, Pécs, PO Box 99, Hungary
,
Nóra M. Bárácz Central Research Laboratory, Chemistry, University of Pécs, H-7643, Pécs, PO Box 99, Hungary
,
Gyula Jerkovich Institute for Drug Research, H-1325, Budapest, PO Box 82, Hungary
&
Kálmán Hideg Central Research Laboratory, Chemistry, University of Pécs, H-7643, Pécs, PO Box 99, Hungary; Chemistry and Biochemistry Department, Janus Pannonius University, H- 7601, Pécs, Hungary
Pages 2929-2940 | Received 30 Jan 1995, Published online: 16 Feb 2007
 
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Abstract

Nitrones and nitroxides were selectively reduced with Fe/AcOH to secondary amines in the presence of different functional groups (aldehyde, nitrile, carboxylic ester, activated and nonactivated double or triple bonds).

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