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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 19
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Original Articles

Selective Acidic Cleavage of Ketals in the Presence of tert-Butyldimethylsilyl Ethers

Pages 2959-2962 | Received 03 Feb 1995, Published online: 16 Feb 2007
 

Abstract

Dilute methanolic HCI in anhydrous THF (<0.5% CH3OH, ca. 10−2 molar H+) cleaves acetals and ketals, whereas t-butyldimethylsilyl ethers where recovered unchanged even at elevated temperatures.

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