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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 19
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Original Articles

Simple, Safe, Large Scale Synthesis of 5-Arylmethyl-2,2-dimethyl-1,3-dioxane-4,6-diones and 3-Arylpropanoic Acids

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Pages 3067-3074 | Received 31 Jan 1995, Published online: 16 Feb 2007
 

Abstract

Reaction of aryl aldehydes with Meldrum's acid 2 in the presence of formic acid and triethylamine gives 5-arylmethyl Meldrum's acid derivatives 4 at room temperature, whereas at 80–100°C 3-arylpropanoic acids 5 are formed.

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