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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 17
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Original Articles

Convenient One-Pot Methodology for the Primary Aminomethylation of Electron Rich Heterocycles

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Pages 2631-2637 | Received 04 Jan 1995, Published online: 23 Sep 2006
 

Abstract

Primary aminomethyl groups were introduced into the 2-position of electron rich heterocycles in moderate to good yields by a one-pot sequence involving lithiation, transmetalation into an organozinc reagent and treatment with 1-(triphenylphosphoroylideneaminomethyl) benzotriazole (betmip).

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