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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 18
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Original Articles

Selective Ketalization of Steroidal 3,11,17-Trione using Chlorotrimethylsilane as Catalyst

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Pages 2807-2811 | Received 13 Feb 1995, Published online: 16 Feb 2007
 

Abstract

Selective ketalization of 13β-ethyl-gona-4-ene-3,11,17-trione (1) using chlorotrimethylsilane as catalyst afforded 13β-ethyl-gona-5-ene-3,11,17-trione-3-ethylene ketal (2) in fairly high yield. The corresponding 3,17-diethylene ketal (3) was obtained in 70% yield when p-toluenesulfonic acid was used as catalyst.

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