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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 25, 1995 - Issue 18
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Original Articles

A Facile One-Pot Transformation of Carboxylic Acids to Amides

Jong Chan Lee Department of Chemistry, Chung-Ang University Seoul, 156-756, Korea
,
Yoon Hwan Cho Department of Chemistry, Chung-Ang University Seoul, 156-756, Korea
,
Hyeok Koo Lee Department of Chemistry, Chung-Ang University Seoul, 156-756, Korea
&
Sung Hye Cho Department of Chemistry, Chung-Ang University Seoul, 156-756, Korea
Pages 2877-2881 | Received 31 Jan 1995, Published online: 16 Feb 2007
 
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Abstract

Carboxylic acids, converted in situ into carboxylic-(p-nitrobenzene)sulfonic anhydrides using p-nitrobenzenesulfonyl chloride, Et3N, and DMAP in CH3CN, react with primary or secondary amines, to give amides in high yields.

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