Synthetis of Pyrrole, and Andpyridinone Pyrimidinone Derivatives Using PTC Conditions

Abstract

The reaction of anilinomethylenemalononitrile 1 or 1,4-di (malononitrilemethyleneamino) benzene 7 with some reactive halo compounds in a one-pot reaction under PTC conditions affords a new series of pyrrole and pyridinone compounds. The reaction of compounds 1 or 7 with ethyl chloroformate gives the corresponding esters which underwent cyclization on reaction with different amino compounds affording the pyrimidinone derivatives.